Edward Calvin Kendall Ph.D.
Edward Calvin Kendall Ph.D.
The Nobel Prize in Physiology or Medicine 1950
Nobel Co-recipients Tadeus Reichstein, Phillip S.Hench
Name: Edward Calvin Kendall
Birth: 8 March 1886, South Norwalk, CT, USA
Death: 4 May 1972, Princeton, NJ, USA
Affiliation at the time of the award: Mayo Clinic, Rochester, MN, USA
Prize motivation: “”for their discoveries relating to the hormones of the adrenal cortex, their structure and biological effects”
Field: Biochemistry, endocrinology
Prize share: 1/3
What physiologic processes are modified by cortisone and how this influence is exerted are matters still locked within this hormone. Said Shakespeare’s soothsayer, “In Nature’s infinite book of secrecy a little I can read.”
Biography
Books
Goal
Eponyms
History of Discovery
Patents
Publications
Books
Summary: In 1948, when “Mrs. G.,” hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound-cortisone-her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought “magic bullet” came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone’s development, and looks at drugs that owe their heritage to the so-called “King of Steroids.”
University of Chicago Round Table
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